The total bacterial count exceeds the standard ≠ All are harmful!
Imbalance of microbiota ≈ Health warning?
Different strains = Vastly different effects!
These seemingly similar terms with the word "bacterium" or "microbiota" actually describe different dimensions of the microbial world as seen by scientists. Misusing them can lead to completely incorrect understanding! It's time to upgrade your cognitive toolbox and stop lumping everything under the term "bacteria." This article will provide you with a crystal-clear framework and relatable analogies, ensuring you easily grasp and remember these concepts.
These six terms are not parallel; they have a clear hierarchy from macro to micro, much like "country-province-city-street-household-residence."
In short, microbiota→genus→species→strain is a process of "group→classification unit→precise individual";
While cells and colonies describe the "living form" and "growth traces" of microbes, falling under the category of "morphological description."
Microbiota: Microbial "Shared House"
Definition: A mixed group of various microorganisms (such as bacteria, fungi) in the same environment.
Key: It doesn't matter if they are of the same species, only that they share the same space.
Examples: Gut microbiota (containing hundreds of species like bifidobacteria, lactobacillus), soil microbiota.
Analogy: A house shared by multiple households.
Genus: Microbial "Family Surname"
Definition: A group of closely related microorganisms with similar characteristics, Latin name capitalized.
Key: "Same surname different names," similar but not identical features.
Examples: Bifidobacterium genus (including Bifidobacterium infantis, Bifidobacterium longum), Influenza virus genus (including types A and B flu viruses).
Analogy: Family surnames like Zhang or Li.
Species: Microbial "Full Name"
Definition: A group with consistent characteristics and stable genetics, Latin name is “genus name + species name” (species name in lowercase).
Key: "Same surname and same name," the basic unit of classification.
Examples: Escherichia coli (E. coli), Saccharomyces cerevisiae (used for baking/brewing).
Strain: Microbial "ID Number"
Definition: Individuals of the same species with slight differences, identified by numbers/letters.
Key: Same species, different strains, vastly different functions.
Examples: E. coli O157:H7 (pathogenic) vs E. coli Nissle 1917 (probiotic); Bifidobacterium lactis BB-12® (BB-12® is the strain number).
Analogy: Same name "Zhang San", but different ID numbers and abilities.
Cell: Microbial "Body"
Definition: The living entity of microorganisms, either unicellular (e.g., bacteria) or multicellular (e.g., mold hyphae).
Key: Not about classification, just the "physical entity" of the bacterium.
Examples: Single E. coli under a microscope, green fuzz on moldy bread.
Analogy: The human body.
Colony: Microbial "Dormitory"
Definition: The visible collection formed by microorganisms growing on a solid medium (like a petri dish).
Key: It's a "growth trace," not the microbe itself; shape (color, size) helps identify the microbe.
Examples: Golden round spots in a petri dish (likely Staphylococcus aureus), milky white layer on yogurt surface.
Analogy: A dormitory where bacteria live collectively.
Term | Core Definition | Key Points | Relatable Analogy |
Microbiota | Mixed Group | Various microbes, Same environment | Shared house (multiple households) |
Genus | Classification unit (large) | Closely related, similar features | Family surname (Zhang) |
Species | Classification unit (specific) | Same characteristics, stable genetics | Full name (Zhang San) |
Strain | Individual differences | Same species, slight differences | ID number (Zhang San No.1) |
Cell | Morphological structure | The microbe itself, living entity | Human body |
Colony | Growth form | Visible to the naked eye, growth trace | Dormitory |
From now on, stop vaguely referring to "bacteria"! By accurately identifying these terms, you can not only understand popular science and choose the right probiotics, but also truly comprehend the incredible and coexistent microcosm with us. Share this article with friends who have been equally confused and become knowledgeable in the field of microbiomes together!

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